BioTE pellets are made from plant-derived compounds (soy or yam) that are purified into estradiol or testosterone. They do not contain soy allergens. Stearic acid is used as a binding agent, and allergic reactions to it are extremely rare.

Pellet therapy has been used since 1939 and was originally developed for women after hysterectomies. It is widely used in Europe and Australia and is one of the most studied forms of hormone replacement therapy.

Bio-identical HRT was widely used until synthetic hormones like Premarin were introduced in the 1940s. Because bio-identical hormones cannot be patented, they receive less promotion from pharmaceutical companies. There is strong research supporting pellet therapy for heart, bone, brain, and breast health. You can explore studies on the BioTE website under “Support” → “Studies.”

The hormones used (estradiol and testosterone) are FDA approved. While the pellet itself is not specifically FDA approved, it is manufactured in FDA-regulated 503B facilities, ensuring strict quality and safety standards.

BioTE pellets are independently tested for quality and consistency. They are sterilized using advanced e-beam technology and produced with very low variation: • ~3% variance for testosterone • ~5% variance for estrogen

The program includes: • Healthy eating • Regular exercise • Recommended supplements Your treatment plan is personalized based on lab results and your health assessment. Additional hormones (like thyroid or progesterone) may be included if needed.

Less than 2% of patients experience true side effects. Some temporary symptoms may occur during the adjustment phase. For women: • Fluid retention (temporary) • Breast tenderness • Irregular bleeding (should always be evaluated) • Sleepiness (often from progesterone timing) • Acne or hair changes (can be managed) For men: • Mild fluid retention • Acne • Increased hair growth • Possible testicular shrinkage and reduced sperm count